An abnormality in the immune system causing inflammation of the lining in the joints and/or internal organs. Rheumatoid arthritis often affects the same joints on both sides of the body and can affect the hands, wrists, feet, knees, ankles, shoulders, neck, jaw, and elbows. The disease may also cause inflammation of internal organs, leading to significant organ damage. Individuals with rheumatoid arthritis are likely to experience times when they have few symptoms and other times when they have very severe symptoms causing significant limitations
